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Newsletter October 9, 2008
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Arthritis: Fractalkine May Be Key to Unleashed Immune Response in Rheumatoid Arthritis
Fractalkine (FKN) is emerging as a central player in the RA synovial inflammation, neovascularization, and joint destruction, and also might be link between joint damage and increased cardiovascular risk...

Arthritis: Rheumatologists Usually on Target With Intra-Articular Injections, Even Without Ultrasound
New research shows that blind intra-articular injections (IAIs) in rheumatoid arthritis patients, done without ultrasound guidance, are accurate when performed by a trained rheumatologist. Blind injections into the ankle are the most unreliable, at 77% accuracy...

Consumer News: Fat Limbs Linked to Disability in Arthritis
Rheumatoid arthritis patients with more fat on their arms and legs suffer a greater degree of disability from their disease than those with thinner limbs...

BioPharm Business: Incyte's Topical JAK Inhibitor Shows Positive Proof-of-Concept Results in Two Phase IIa Clinical Trials in Patients with Mild-to-Moderate Psoriasis; Phase IIb Expected to Start October 2008
Results from the first study demonstrated that INCB18424 was well tolerated at all doses and significantly improved overall total lesion score (erythema + scaling + thickness)...